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Urofollitropin

What is Urofollitropin used for?

USES:

Urofollitropin is used with other medication for the following underlying conditions:

  • to treat infertility in women
  • to induce ovulation
  • to treat hypogonadism
  • It is also used in IVF (in-vitro fertilization) as it helps in producing multiple eggs from the ovaries.

IUPAC name: (2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-13-[(2S)-butan-2-yl]-10-[(1R)-1-hydroxyethyl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide

Drug class: Gonadotropins

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Route of administration: Subcutaneous, Intramuscular

Is it a drug that needs a prescription? YES

Is it an OTC drug? NO

Mechanism of action

Urofollitropin  acts similar to follicle-stimulating hormone (FSH) and it is used by women who produce insufficient amounts of FSH. Thus, it helps in the growth and maturation of eggs in the ovaries and production of gonadal steroid hormones.

Side effects

Common side effects may include nausea/vomiting, bloating, pain in stomach, breast tenderness, weakness, swelling of face, lips, tongue

Serious side effects may include swelling of ankles/feet/hands, abnormal vaginal bleeding, pain in chest, change in vision, shortness of breath, swelling/pain in abdominal area, weight gain, rash/itching, trouble breathing,

It may cause ovarian hyperstimulation syndrome.

Precautions

Following precautions should be taken before using this medication:

If you are allergic to FSH or if you have any other allergies.

If you have a medical history of breast/uterus/ovary cancer, irregular vaginal bleeding, brain tumor, heart attack, asthma, stroke, thyroid problem, adrenal gland problem, ovarian cyst, PCOS, blood clots, thrombophilia.

Use of this medication may cause multiple births.

This medication should not be used during pregnancy.

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