Tropisetron, an Antiemetic Drug


This medication is used to treat nausea and vomiting associated with cancer treatment (chemotherapy) and surgery.

 IUPAC Name: [(1R,5S)-8-methyl-8-azabicyclo [3.2.1] octan-3-yl] 1H-indole-3-carboxylate

Drug Class: 5-HT3 Receptor antagonist

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 Route of administration: Intravenous or Oral

 This is a prescribed drug, not an OTC drug

Drug Action Mechanism 

This medicine is an antiemetic. It works by blocking serotonin (a chemical messenger in the brain) from causing nausea and vomiting. 


It is advisable to consult a doctor or physician before taking this medication. 

  •  If the person is allergic to the drug or other antiemetic medications (such as
  • ondansetron, granisetron) or have any other allergies, 
  •  If the person is taking any prescribed, non-prescribed or any herbal medications,
  •  If the person is suffering from hepatic disease, cardiac disease, abnormal heart rate, disease the elated to stomach or intestines,
  • If the person has low magnesium, potassium, or sodium levels, the person may be more likely to experience QT prolongation (extended intervals between cardiac contraction and relaxation) when taking this medication.
  • If patient has undergone any type of surgery, i.e., eye or ear surgery,
  • It should not be taken during pregnancy and breastfeeding is also not allowed if the mother is taking tropisetron.

    Adverse Effects

Tropisetron side effects include tiredness, headache, dizziness, and irregular heart rate.

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