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Triflupromazine

Uses

This medication is intended to curb aggressive behavior during acute psychotic episodes.

Additionally, it is used to treat severe hiccups, vomiting, and nausea.

IUPAC name: N,N-dimethyl-3-[2-(trifluoromethyl)phenothiazin-10-yl]propan-1-amine

Drug class: Typical antipsychotics; Phenothiazine

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Route of administration: Oral

Is it a drug that needs a prescription? YES

Is it an OTC drug? NO

Mechanism of action

Both an antipsychotic and an antiemetic effect are produced by this drug. Dopamine, one of the brain’s neurotransmitters, is inhibited as it works to improve thoughts, feelings, moods, and behavior.

Side effects

It may cause dizziness, dry mouth, drowsiness, postural hypotension, constipation, unsteadiness, loss of appetite, sleeping problems, fatigue, nausea, vision problems, and headache.

Precautions

Before using this medication, take the following precautions and notify your doctor:

If you are allergic to it or to other antipsychotic (neuroleptic) drugs, or if you have any other allergies,

If you are taking any other medication (prescribed, non-prescribed, or herbal products),

If you have a history of hepatic disease, kidney problems, cardiac disease (arrhythmia, angina, heart attack), hypotension (low blood pressure), glaucoma, seizures, lung/breathing problems, breast cancer, blood cell disorders ( anemia, leukemia, bone marrow depression, thrombocytopenia), enlarged prostate gland, pheochromocytoma, Parkinson’s disease, drug or alcohol abuse, 

If you have undergone any type of surgery, 

Since this drug increases your sensitivity to the sun, avoid spending time outside in the sun while taking it.

Limit your alcohol usage since it increases your chances of developing blurred vision, dizziness, or drowsiness. It may also cause a loss of alertness.

This drug’s adverse effects are more severe in older adults with dementia.

Avoid activities that can cause you to overheat while taking this medication.

If you are pregnant, talk to your doctor. Using this drug in the last trimester of pregnancy is not recommended since it might harm the unborn child. 

Consult your doctor if you are breastfeeding.

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