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Tacrine

Uses

This drug is prescribed for the treatment of dementia associated with Alzheimer’s disease.

IUPAC name: 1,2,3,4-tetrahydroacridine-9-anime

Drug class: Cognition enhancers; cholinesterase inhibitor

Route of administration: Oral

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Is it a drug that needs a prescription? YES

Is it an OTC drug? NO

Mechanism of action

This medicine inhibits acetylcholinesterase. It enhances memory and thinking by raising the levels of acetylcholine (a neurotransmitter) in the brain. 

Side effects

It may result in a variety of side effects, including dizziness, lack of coordination, nausea, vomiting, diarrhea, abdominal discomfort, indigestion, weight loss, tremors, exhaustion, weakness, pain in stomach, and seizures.

Precautions

Before using this medication, take the following precautions and notify your doctor:

If you are allergic to it or to other cerebroactive drugs, or if you have any other allergies,

If you are taking any other medication (prescribed, non-prescribed, or herbal products),

If you have a history of lung/breathing issues (COPD-chronic obstructive pulmonary disease, asthma, sleep apnea), cardiac disease, ulcers, irregular heart rate, heart rhythm disorder, hepatic disease, kidney problems, seizures (fits), urinating problems,

You can experience adverse effects that affect how you think or act.

Tacrine may increase the risk of QT prolongation if you have certain cardiac diseases (bradycardia, arrhythmia or QT prolongation).

If you have undergone any type of surgery,

Limit your alcohol usage since it increases your chances of developing blurred vision, dizziness, or drowsiness. It may also cause a loss of alertness.

Avoid abruptly discontinuing this medication without first talking to your doctor.

If you are pregnant, talk to your doctor. 

Consult your doctor if you are breastfeeding.

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