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Sorafenib

Uses

This anticancer drug is used for the treatment of following conditions:

  •  hepatoma (cancer of the liver cells)
  •  renal cell carcinoma (cancer of the kidney cells) 
  •  thyroid cancer

IUPAC name: 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methylpyridine-2-carboxamide

Drug class: Antineoplastic; Tyrosine Kinase inhibitor

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Route of administration: Oral

Is it a drug that needs a prescription? YES

Is it an OTC drug? NO

Mechanism of action

Sorafenib is a tyrosine kinase inhibitor that inhibits cancerous cell development and proliferation by blocking the action of an aberrant protein that signals cancer cells to multiply.

Side effects

Nausea, vomiting, dry skin, hair loss, weight loss, diarrhea, loss of appetite, sore mouth, taste changes, tiredness, weakness, dry mouth, pain in joints, redness, swelling, blisters or pain in the hands or feet, rash/itching.

Precautions

Before using this medication, take the following precautions and notify your doctor:

  • If you are allergic to it or have any other allergies,
  • If you are taking any other medication (prescribed, non-prescribed, or herbal products),
  • If you have a medical history heart disease (including coronary artery disease, irregular heart rate, heart attacks), bleeding issues, hypertension (high blood pressure), kidney problem, hepatic disease, severe dizziness, low levels of magnesium or calcium in blood,
  • If you have any recent surgery,
  • This medication should not be given if you are pregnant or intend to become pregnant.
  • If you are breastfeeding, you should consult the doctor.

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