Individuals with type 2 diabetes can use this medication to manage high blood sugar levels (hyperglycemia). Depending on the patient’s condition, it can be used alone or with other medications, along with a balanced diet (appropriate diet and exercise).
IUPAC name: (3R)-3-amino-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one
Drug class: Anti-diabetic drug; Dipeptidyl peptidase-4 (DPP-4) inhibitor
Route of administration: Oral
Is it a drug that needs a prescription? YES
Is it an OTC drug? NO
Mechanism of action
The drug inhibits DPP-4, an enzyme that destroys incretin. This leads to higher level of incretins. Incretins help to control blood sugar by increasing insulin release only when it is necessary and by reducing the amount of sugar or glucose produced by the liver.
Sitagliptin may cause nausea, headache, diarrhea, vomiting, sore throat, stomach discomfort, itching, rash, blistering of the skin, sweating, dizziness, low blood sugar level (hypoglycemic).
Before using this medication, take the following precautions and notify your doctor:
If you are allergic to it or have any other allergies,
If you are taking any other medication (prescribed, non-prescribed, or herbal products),
It is not used to treat individuals with type 1 diabetes.
If you have a history of renal or cardiac disease, swelling of the pancreas, diabetic ketoacidosis, a high level of triglycerides in the blood, gallstones,
If you have undergone any type of surgery,
It should not be used by type 1 diabetic patients.
Limit your alcohol usage since it increases your chances of obtaining low blood sugar levels. It may also cause headaches, vomiting, nausea, flushing, disorientation, and anxiety.
You may have dizziness, changes in vision, or lack of awareness as a result of low or high blood sugar levels.
When your body is stressed, controlling your blood glucose level becomes challenging.
Consult your doctor if you get pregnant or if you are breastfeeding while using this medication.
Consult your doctor in the case of pregnancy.