Ramosetron, an Antiemetic Drug


The medicine alleviates nausea, vomiting, as well as diarrhoea.

  IUPAC Name: (1-methylindol-3-yl)-[(5R)-4,5,6,7-tetrahydro-3H-benzimidazol-5-yl] methanone

 Drug Class: 5-HT3 Receptor antagonist

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Route of administration: Oral and Intravenous

 This is a prescribed drug, not an OTC drug

Drug Action Mechanism 

This medicine is an antiemetic. It works by preventing serotonin (a chemical messenger in the brain) from causing nausea and vomiting.


It is advisable to consult a doctor or physician before taking this medication. 

  •   If the person is allergic to this drug or other antiemetic medications (such as ondansetron, palonosetron) have any other allergies, 
  •  If the person is taking any prescribed, non-prescribe any herbal medications,
  •  If the person is suffering from hepatic disease, cardiac disease, abnormal heart rate, disease the elated to stomach or intestine ines,
  •  If patient has undergone any type of surgery i.e., eye or ear surgery, 
  •  Limit the usage of alcohol since it increases the chances of developing blurred vision, dizziness, or drowsiness. It may also cause a loss of alertness.
  • Ramosetron may increase the risk of QT prolongation if a person has certain cardiac diseases (bradycardia, heart failure, or QT prolongation).
  • If a person has low blood levels of magnesium, potassium, or sodium, he/she may be more likely to experience QT prolongation (extended intervals between cardiac contraction and relaxation) when taking this medication.
  • The adverse effects of this medication may affect elder people more severely.
  • Consult a doctor if the person is pregnant or breastfeeding. 

 Adverse Effects

 Ramosetron’s side effects include constipation, headache, dizziness, and fever.

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