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Quinapril, Angiotensin Converting Enzyme Inhibitor

Uses

The drug is prescribed to treat Hypertension (high blood pressure). In addition, it helps to prevent heart attacks, strokes and congestive heart failures.

IUPAC Name: (3S)-2-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl] amino] propanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxylic acid

Drug Class: ACE Inhibitor

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Route of administration: Oral 

This is a prescribed drug and not an OTC Drug

Drug Action Mechanism 

  • This medication is an Angiotensin Converting Enzyme (ACE) Inhibitor. It works by inhibiting an enzyme that causes blood vessels to constrict.
  • It functions by relaxation of blood vessels (i.e., arteries and veins) and lowering heart pressure, allowing blood to flow more smoothly and the heart to pump blood more efficiently.   

Side Effects 

Quinapril side effects include dizziness, coughing, exhaustion, nausea, hypotension (decreased blood pressure), and elevated potassium levels.

Warning

Avoid using this medication, if the person is pregnant. Consult a doctor if the person becomes pregnant while administering this medication since it might cause damage to the developing fetus.

Precautions

Before using this medication, follow these precautions and notify your doctor

  • If the person is allergic to the drug or other ACE inhibitors (such as enalapril, lisinopril, captopril, benazepril, moexipril), or if the person has other allergies.
  • If the person is having prescribed, non-prescribed or herbal medication.
  • If the person is suffering from any cardiac disease, hepatic disease, renal disease, hypotension (low blood pressure), diabetes, angioedema, scleroderma, lupus or a high blood potassium level.
  • There might be an increase in potassium levels if one uses this medication. Avoid potassium-rich substitutes. 
  • If the person has undergone any type of surgery i.e., eye or dental surgery, 
  • While taking this medication, limit alcohol usage since it increases the chances of developing blurred vision, dizziness or drowsiness. It may also cause a loss of alertness.
  • The person should be aware that dehydration, vomiting, excessive perspiration and diarrhoea can lower blood pressure which leads to dizziness.
  • Avoid abruptly discontinuing this medication without a doctor consultation. The adverse effects of this medication may affect elder people more severely.
  • Consult a doctor if the person is pregnant and breastfeeding. 

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