Pramlintide (Symlin)

USES

Individuals with Type 1 and Type 2 diabetes take the injection to control their blood sugar levels.

IUPAC name: (2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-4-amino-1-[[(2S)-1-[[2-[(2S)-2-[[(2S,3S)-1-[[(2S)-1-[(2S)-2-[(2S)-2-[[(2S,3R)-1-[[(2S)-4-amino-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-4-amino-1-[[(2S,3R)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]pyrrolidin-1-yl]-4-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-imidazol-4-yl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]-2-[[(2S,3R)-2-[[(2S)-2-[[(4R,7S,10S,13S,16S,19R)-16-(2-amino-2-oxoethyl)-19-[[(2S)-2,6-diaminohexanoyl]amino]-7,13-bis[(1R)-1-hydroxyethyl]-10-methyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]amino]propanoyl]amino]-3-hydroxybutanoyl]amino]pentanediamide

Route of administration: Subcutaneous

Drug class: Anti-diabetic drug; amylin analogue

Is it a prescription drug? YES

Is it an OTC drug? NO

Mechanism of action

 It works by delaying digestion and absorption of food, so blood glucose levels stay stable after meals. It may also reduce hunger and aid in weight loss.

Side effects

Common side effects include nausea, vomiting, loss of appetite, abdominal pain, redness/pain/swelling at the site of injection, weakness, dizziness, joint pain, low blood sugar level, shakiness, blurred vision, abnormally fast heartbeat, rash/itching.

Precautions

Before using this medication, take the following precautions and inform your doctor:

If you are allergic to it or have any other allergies,

If you are taking any other medication (prescribed, non-prescribed, or herbal products),

If you have a history of intestinal disorders, ulcer, abdominal pain, gastric problems,

Limit your alcohol usage since it increases your chances of obtaining low blood sugar levels. It may also cause headaches, vomiting, nausea, flushing, disorientation, and anxiety.

You may have dizziness, changes in vision, or lack of awareness as a result of low or high blood sugar levels.

When your body is stressed, controlling your blood glucose level becomes challenging.

Consult your doctor if you get pregnant or if you are breastfeeding while using this medication.

In the case of pregnancy, consult the doctor.