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Pitavastatin, a remedy for heart strokes

Brand Name:  Pivasta · Pitava · Pitezo · Diabastat · Pitadek

Uses

The drug is prescribed along with a healthy diet, it reduces bad cholesterol (LDL) and other fatty acid compounds (such as triglycerides) in the blood while increasing good cholesterol (HDL). Improving the levels of cholesterol in the blood helps to reduce the risk of heart attack or stroke.

IUPAC name: (E,3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl) quinolin-3-yl]-3,5-dihydroxyhept-6-enoic acid

Drug class: Hypolipidaemic drug

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Route of administration: Oral 

This is a prescribed drug and not an OTC drug

Drug action mechanism

Pitavastatin is an HMG-CoA reductase inhibitor (statin). It functions by preventing the production of HMG-CoA-reductase, an enzyme essential for the body to create cholesterol. As a result, it reduces triglycerides and LDL cholesterol while increasing HDL cholesterol (HDL).

Adverse effects

Pitavastatin’s side effects include diarrhoea, nausea, vomiting, constipation, tiredness, body pain, weakness, yellowing of skin or eyes, stomachache, and muscle pain.

Precautions

It is advisable to consult a doctor or physician before taking this medication. 

  • Avoid the usage of this medication, if the patient is allergic to this drug, or has any other allergies if the patient is on any other medication (i.e., prescribed, non-prescribed or usage of any herbal products) if the patient suffers from a hepatic disease, renal issues, thyroid disorder i.e., hypothyroidism 
  • While taking this drug, avoid alcohol consumption as it leads to liver damage. Avoid the usage of this medication, if the patient has undergone any type of surgery i.e., dental or eye surgery. This medication has adverse effects on old people
  • This medication is not recommended for pregnant or breastfeeding women.

    Pitavastatin side effects 

    Get emergency medical help if the patient has signs of an allergic reaction: hives; difficulty breathing; swelling of face, lips, tongue and throat.In rare cases, pitavastatin can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Consult a doctor right away if experiencing unexplained muscle pain, tenderness, or weakness, especially with fever, or unusual tiredness.

    Consult a doctor if experiencing

    • confusion, and memory problems.
    • muscle weakness in hips, shoulders, neck, and back.
    • trouble lifting arms, trouble climbing or standing.
    • if experiencing kidney problems with vomiting, pain on the side, lower back, little or no urinating, swelling, rapid weight gain; or
    • liver problems with loss of appetite, stomach pain (on the upper right side), tiredness, dark urine, clay-coloured stools, and jaundice.

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