The drug is prescribed to prevent angina (decreased cardiac blood flow causing chest discomfort).

IUPAC name: 2-(pyridine-3-carbonylamino)ethyl nitrate

Drug class: Anti-anginal drug; Vasodilator; potassium channel opener

Route of administration: Oral, intravenous

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Is it a drug that needs a prescription? YES

Is it an OTC drug? NO

Mechanism of action

This medication works by relaxing or widening the blood vessels, which lowers the heart’s need for oxygen and lessens the burden on the heart, preventing angina (heart-related chest discomfort).

Side effects

Nicorandil’s adverse effects might include headaches, nausea, vomiting, flushing, dizziness, stomach/abdominal discomfort, ulcers, and palpitations.


Before using this medication, take the following precautions and notify your doctor:

If you are allergic to it or to other anti-anginal drugs, or if you have other allergies,

If you are taking any other medication (prescribed, non-prescribed, or herbal products),

If you have or ever had a heart attack or other cardiac disease, hepatic disease, renal issues, hypotension (low blood pressure), lung disease,

If you have undergone any type of surgery,

While taking this medication, limit your alcohol usage since it increases your chances of developing blurred vision, dizziness, or drowsiness. It may also cause a loss of alertness.

Avoid abruptly discontinuing this medication without consulting your doctor.

The adverse effects of this medicine may affect older people more severely.

Consult your doctor if you are pregnant or breastfeeding.

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