This anticancer drug is used for the treatment of squamous non-small cell lung carcinoma that has progressed to other areas of the body.

Drug class:  Antineoplastic agent; monoclonal antibody 

Route of administration: Intravenous

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Is it a drug that needs a prescription? YES

Is it an OTC drug? NO

Mechanism of action

Necitumumab binds to the epidermal growth factor receptor (EGFR) present on normal as well as cancerous cells. This chemotherapy drug works by blocking this receptor and preventing the growth and proliferation of cancerous cells. 

Side effects

Nausea, vomiting, diarrhea, acne, weight loss, dry skin, sore mouth/throat, vision changes, rash, itching, chest pain, weakness, dizziness.


Take the following precautions before using this drug and notify your doctor:

  • If you are allergic to it, or if you have any other allergies,
  • If you are taking any other medications (prescribed, non-prescribed, or herbal products),
  • If you have a medical history of hypertension, cardiac disease, blood clots, stroke,
  • Avoid prolonged exposure to sunlight during treatment.
  • Use of this medication is not recommended during pregnancy.
  • Breastfeeding should be avoided while the treatment is going on and for the next few months after stopping the use of this drug.
  • You should not become pregnant while taking this drug. If you plan to get pregnant, consult your doctor.

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