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Mobocertinib

Uses

This drug is used to treat non-small cell lung cancer in people who have specific EGFR mutation.

IUPAC name: propan-2-yl 2-[4-[2-(dimethylamino)ethyl-methylamino]-2-methoxy-5-(prop-2-enoyl amino)anilino]-4-(1-methylindole-3-yl)pyrimidine-5-carboxylate

Drug class: Antineoplastic; kinase inhibitor

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Route of administration: Oral

Is it a drug that needs a prescription? YES

Is it an OTC drug? NO

Mechanism of action

Mobocertinib functions as an EGFR tyrosine kinase inhibitor, decreasing or inhibiting cancer cell growth and proliferation by inhibiting aberrant EGFR signaling pathways.

Side effects

Nausea, vomiting, diarrhea, dry skin, loss of appetite, inflammation in the mouth, dry mouth, rash, itching, stomatitis, changes in nails, hair loss temporarily, trouble breathing, changes in eyesight, dizziness, fainting, and chest discomfort are all possible adverse effects of mobocertinib.

Precautions

Before using this medication, take the following precautions and notify your doctor:

  • If you are allergic to it or have any other allergies,
  • If you are taking any other medication (prescribed, non-prescribed, or herbal products),
  • If you have a medical history of abnormally fast heart rate (QT prolongation), cardiac disease, low levels of potassium or magnesium in the blood,
  • If you have had any recent surgery,
  • You should not get pregnant while taking this medication.
  • This medication is not recommended during pregnancy.
  • Breastfeeding should be avoided while the treatment is going on and for the next 7 days after stopping the use of this drug.

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