Methimazole, a hyperthyroidism drug


The drug is prescribed for the treatment of hyperthyroidism (overactive thyroid) as well as before thyroid surgery or radioactive iodine therapy.

IUPAC name: 3-methyl-1H-imidazole-2-thione

Drug Class: Antithyroid drugs

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Route of administration: Oral 

This is a prescribed drug and not an OTC drug 

Drug Mechanism Action 

This medication prevents the thyroid gland from producing an excessive amount of thyroid hormone.

Adverse effects

The adverse effects of methimazole include nausea, vomiting, stomach/abdominal pain, dizziness, pain in muscles or joints, rash/itching, hair loss, sore throat, swelling, prickling or tingling sensation.


It is advisable to consult a doctor or physician before taking this medication. 

  • If the person is allergic to the drug or has any other allergies 
  • If the person is taking any medication (i.e., prescribed, non-prescribed or any herbal medication)
  • If the person is suffering from hepatic disease, low blood platelet count or any other blood disorder, weak immunity
  • While taking this drug, avoid alcohol consumption because it elevates the chance of developing hepatic issues.
  • If the person has undergone any type of eye surgery or dental surgery.
  • This medication is recommended for pregnant women in the first three months of pregnancy and later it is not recommended for use. Methimazole is not advised while breastfeeding.
  •  Methimazole should not be given to a child without a doctor’s advice.

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