Memantine, a Cognition Enhancer


This drug is prescribed to manage moderate to severe dementia associated with Alzheimer’s disease.

IUPAC Name: 3,5-dimethyl adamantane-1-amine

Drug Class: Cognition enhancers; Glutamate (NMDA) antagonist

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Route of administration: Oral

This is a prescribed drug and not an OTC Drug

Drug Action Mechanism

This medication works by inhibiting the NMDA (N-methyl-D-aspartate) receptors in the brain, which helps to enhance memory, thinking, consciousness and the capacity to conduct everyday duties.

 Side Effects

It may result in a variety of side effects, including dizziness, headache, sedation, constipation, nausea, body aches, confusion, lack of balance, weight gain and hypertension.


Before using this medication, take the following precautions and notify the doctor:

  • If the person is allergic to the drug or other drugs, or if the person has any other allergies,
  • If the person is taking any other medication (prescribed, non-prescribed, or herbal medication),
  • If the person has or ever had kidney disease, hepatic issues, a urinary tract infection, seizures,
  • If the person has undergone any type of surgery i.e., eye or ear surgery, 
  • Limit alcohol usage since it increases the chances of developing blurred vision, dizziness, or drowsiness. It may also cause a loss of alertness.
  • Consult a doctor if the person is pregnant or breastfeeding.


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