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Loxapine

Uses

This drug is prescribed for schizophrenia treatment.

IUPAC name: 8-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine

Drug class: Typical antipsychotics

Route of administration: oral, intramuscular, inhalation

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Is it a drug that needs a prescription? YES

Is it an OTC drug? NO

Mechanism of action

This medication works by inhibiting the activity of a neurotransmitter (dopamine) in the brain and helps to enhance thoughts, feelings, moods, and behavior.

Side effects

It may cause dizziness, drowsiness, dry mouth, headache, vision problems, weight gain, constipation, nausea, fatigue, salivation, agitation, postural hypotension, muscle cramps, tremors, and trouble swallowing.

Precautions

Before using this medication, take the following precautions and notify your doctor:

If you are allergic to it or to other antipsychotic (neuroleptic) drugs, or if you have any other allergies,

If you are taking any other medication (prescribed, non-prescribed, or herbal products),

If you have a history of stroke, cardiac disease (arrhythmia, heart attack, heart failure), glaucoma, seizures (fits), liver disease, lack of body balance, difficulty urinating, breast cancer, Parkinson’s disease, blood disorders (anemia, leukemia, thrombocytopenia), drug or alcohol abuse,

If you have ever had reactions to other antipsychotic medications,

If you have undergone any type of surgery,

Since this drug increases your sensitivity to the sun, avoid spending time outside in the sun while taking it.

Limit your alcohol usage since it increases your chances of developing blurred vision, dizziness, or drowsiness. It may also cause a loss of alertness.

Avoid abruptly discontinuing this medication without first talking to your doctor.

This drug’s adverse effects are more severe in older adults with dementia.

Avoid activities that can cause you to overheat while taking this medication.

If you are pregnant, talk to your doctor. Using this drug in the last trimester of pregnancy is not recommended since it might harm the unborn child.

Consult your doctor if you are breastfeeding.

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