Lenvatinib Mesylate

Uses

This medicine is prescribed to address the following underlying conditions:-Endometrial cancer that has progressed

• Thyroid cancer with distinct subtypes
• renal cell cancer (advanced kidney cancer)
• hepatocellular malignancy (a type of liver cancer)

IUPAC name: 4-[3-chloro-4-(cyclopropyl carbamoylamino)phenoxy]-7-methoxyquinoline-6-carboxamide;methanesulfonic acid

Drug class:  Tyrosine Kinase Inhibitor

Route of administration: Oral

Is it a drug that needs a prescription? YES

Is it an OTC drug? NO

Mechanism of action

Lenvatinib works by blocking the numerous tyrosine kinase receptors that signal cancer cells to proliferate. This helps in the prevention of cancer cell growth.

Side effects

Side effects may include high blood pressure (hypertension), nausea, tiredness, headache, muscle pain, diarrhea, skin peeling, decreased appetite, sore mouth, weight loss, joint pain, rashes, itching, redness of skin, hair loss, insomnia, seizures, coughing, vomiting, pale skin, swelling of legs or ankles, shortness of breath, dark color urine, difficulty in speech, swelling of mouth or lips, dizziness, taste change.

Precautions

Take the following precautions before using this drug and notify your doctor:

If you are allergic to it or if you have any other allergies,

If you are taking any other medications (prescribed, non-prescribed, or herbal products),

If you have a medical history of hypertension, heart attack, stroke, abnormal heart rate, severe headache, vision changes, unconsciousness or fainting, low levels of magnesium, potassium or calcium, seizures, thyroid disease, hepatic disease, renal problems, dental problems,

If you are going to have any surgery,

It may cause jawbone problem,

Use of this medication is not recommended during pregnancy or breastfeeding.

Do not get pregnant while using this medicine, use an effective form of birth control.