Isosorbide mononitrate


The drug is prescribed to prevent angina (decreased cardiac blood flow causing chest discomfort).

IUPAC name: [(3S,3aR,6R,6aS)-3-hydroxy-2,3,3a,5,6,6a-hexahydro furo[3,2-b]furan-6-yl] nitrate

Drug class: Nitrate vasodilator

Route of administration: Oral

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Is it a drug that needs a prescription? YES

Is it an OTC drug? NO

Mechanism of action

 It functions by relaxing or widening the blood vessels, which lowers the heart’s need for oxygen and lessens the burden on the heart, preventing angina (heart- related chest discomfort).      

Side effects

It could result in lightheadedness, dizziness, nausea, headache, flushing, vision problems, postural hypotension, and palpitations.


Before using this medication, take the following precautions and notify your doctor:

If you are allergic to it or to other nitrates, or if you have other allergies,

If you are taking any other medication (prescribed, non-prescribed, or herbal products),

If you have or ever had a heart attack or other cardiac disease (such as congestive heart failure), anemia (low red blood cells), hypotension (low blood pressure), abnormally fast heart rate, head injury, dehydration, stomach cramps,

If you have undergone any type of surgery,

While taking this medication, limit your alcohol usage since it increases your chances of developing blurred vision, dizziness, or drowsiness. It may also cause a loss of alertness.

Avoid abruptly discontinuing this medication without consulting your doctor.

The adverse effects of this medicine may affect older people more severely.

Consult your doctor if you are pregnant or breastfeeding.

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