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Iloperidone

Uses 

This drug is prescribed to treat schizophrenia. 

IUPAC name: 1-[4-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propoxy]-3-methoxyphenyl]ethanone

Drug class: Atypical antipsychotics

Route of administration: Oral

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Is it a drug that needs a prescription? YES

Is it an OTC drug? NO

Mechanism of action

This medication works by regulating and restoring the activity of certain neurotransmitters (such as dopamine and serotonin) in the brain and helps to enhance thoughts, feelings, moods, and behavior.

Side effects

It may cause dizziness, drowsiness, dry mouth, headache, fatigue, weight gain, nausea, abdominal pain, restlessness, postural hypotension, and sedation.

Precautions

Before using this medication, take the following precautions and notify your doctor:

If you are allergic to it or to other antipsychotic (neuroleptic) drugs, or if you have any other allergies,

If you are taking any other medication (prescribed, non-prescribed, or herbal products),

If you have a history of stroke, cardiac disease (arrhythmia, heart attack, heart failure), leukemia (low white blood cell), liver disease, kidney problems, breast cancer, obesity, seizures, diabetes, high cholesterol, difficulty swallowing, sleep apnea, dehydration, dementia, 

If you have undergone any type of surgery,

Iloperidone may increase the risk of QT prolongation if you have certain cardiac diseases (bradycardia, heart failure, or QT prolongation).

If you have low blood levels of magnesium, potassium, or sodium, you may be more likely to experience QT prolongation (extended intervals between cardiac contraction and relaxation) when taking this medication.

Limit your alcohol usage since it increases your chances of developing blurred vision, dizziness, or drowsiness. It may also cause a loss of alertness.

Avoid abruptly discontinuing this medication without first talking to your doctor.

This drug’s adverse effects are more severe in older adults with dementia.

Avoid activities that can cause you to overheat while taking this medication.

If you are pregnant, talk to your doctor. Using this drug in the last trimester of pregnancy is not recommended since it might harm the unborn child.

Consult your doctor if you are breastfeeding.

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