The following underlying conditions are treated with alendronate:

  1. Osteoporosis in women after menopause
  2. Osteoporosis as a result of corticosteroid use for an extended period of time

IUPAC name: hydroxy-[1-hydroxy-3-[methyl(pentyl)amino]-1-phosphonopropyl]phosphinate

Drug class: Bisphosphonates

Route of administration: Oral, Intravenous

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Is it a drug that needs a prescription? YES

Is it an OTC drug? NO

Mechanism of action
Ibandronate is a drug that is used to avert osteoclast activity (bone resorption). As a result, it works by improving bone mineral density and lowering the chance of bone breakdown (fractures).

Side effects
Nausea, stomach pain, diarrhea, constipation, bloating, headache, dizziness are some of the most common side effects.

Serious side effects may include swelling of joints/hands/legs/ankles, severe pain in joints/bone/muscle, abdominal pain, pain in chest, jaw pain, black/tarry stool, heartburn, pain in groin/thighs/hips, ulcers in esophagus/stomach, vision changes, rash/itching/hives.


Before using this medication, take the following precautions and notify your doctor:

  • If you are allergic to bisphosphonates (such as alendronate, pamidronate, risedronate) or any other allergens.
  • If you have a history of achalasia (esophageal disorder), difficulty swallowing, hypocalcemia, kidney disease, or ulcers, painful swallowing.
  • If you can’t sit or stand straight for at least 60 minutes.
  • If you have a jawbone problem or pain.
  • If you are pregnant or nursing.

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