This medication is used for the treatment of the following underlying conditions:

  • Advanced breast cancer
  • Endometriosis (uterus disorder)
  • Abnormal uterine bleeding
  • Prostate cancer
  • It is also used to make the inner wall of uterus thinner

IUPAC name:  (2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[(carbamoylamino)carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-[(2-methylpropan-2-yl)oxy]-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide

Drug class: Gonadotropin-releasing hormone agonists

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Route of administration: Subcutaneous

Is it a drug that needs a prescription? YES

Is it an OTC drug? NO

Mechanism of action

It is the analogue of luteinizing hormone-releasing hormone (LHRH). It works by binding to the gonadotropin releasing hormone receptors and prevents the gonadotropin secretion. Thus production of testosterone in men and estrogen in women has been decreased.

Side effects

Common side effects may include dizziness, hot flashes, headache, sweating, difficulty in sleeping, vaginal itching/dryness, nausea, pain/swelling at the site of injection, change in breast size.

Serious side effects may include itching/rash/hives, pain in chest, trouble breathing, vaginal burning, bone pain, swelling of hand/feet/ankles, depression, tiredness/weakness, painful urination, abdominal pain, blurred vision.


Following precautions should be taken before using this medication:

  • If you are allergic to LHRH, triptorelin or if you have other allergies.
  • If you are taking other medications (prescription medicine, nonprescription medicine and herbal products).
  • If you have a medical history of irregular vaginal bleeding, diabetes, osteoporosis, heart attack, strokes, high cholesterol level, prolonged intake of alcohol or smoking.
  • It may affect the heart rhythm (QT prolongation). Decreased potassium/magnesium level may increase the risk of the QT prolongation.
  • It should not be used during pregnancy.

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