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Gefitinib

Uses

This medication is used by patients with metastatic non-small cell lung cancer (cancer that has spread to other parts of the body). 

IUPAC name: N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-yl propoxy) quinazolin-4-amine

Drug class: Antineoplastic; Tyrosine Kinase inhibitor

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Route of administration: Oral

Is it a drug that needs a prescription? YES

Is it an OTC drug? NO

Mechanism of action

Gefitinib works as an EGFR tyrosine kinase inhibitor, reducing or preventing the growth and proliferation of cancerous cells by blocking abnormal EGFR signaling pathways.

Side effects

Nausea, vomiting, dry skin, diarrhea, decreased appetite, acne, sore mouth, weakness,  loss of appetite, headache, dizziness, rash/itching, weight loss, hair loss, dehydration.

Precautions

Before using this medication, take the following precautions and notify your doctor:

  • If you are allergic to it or have any other allergies,
  • If you are taking any other medication (prescribed, non-prescribed, or herbal products),
  • If you have a medical history of intestinal or stomach ulcers, hepatic disease, renal disease, eye issues, bowel disease, indigestion, heartburn,
  • Consult your doctor if you are pregnant or intend to become pregnant.
  • This medication should not be given during pregnancy as it may harm the baby.
  • If you are breastfeeding, you should not use this drug.

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