This medication is used to treat endometriosis which causes pelvic pain and infertility in women.

It is used to treat fibrocystic breast disease (non-cancerous cysts make the breast feel lumpy).

It is also used to prevent angioedema attacks.

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IUPAC name:  17α-ethynyl-17β-hydroxyandrost-4-en-[2,3-d]isoxazole, 

Drug Class: Androgenic hormone

Is it a drug that needs a prescription? YES

Is it an OTC drug? NO


Danazol works by decreasing the amount of follicle-stimulating hormone and luteinizing hormone made by ovaries as these hormones make the condition worse.

It also works by enhancing the amount of a certain protein in your body’s defense system to treat angioedema.


Common side effects may include:

  • weight gain
  • acne
  • sweating
  • flushing
  • vaginal dryness, irritation, itching, burning
  • decrease in breast size
  • abnormal body hair growth
  • change in the menstrual cycle
  • nervousness
  • swelling in feet, ankles, or hands


Before using this drug, tell your doctor:

If you are allergic to it or any other drug or if you have any other allergies.

If you have a medical history of porphyria, stroke, coronary artery disease, hypertension, high level of cholesterol, diabetes, liver/kidney disease, abnormal vaginal bleeding, migraine, seizures.

During pregnancy, the use of this medicine should be avoided as it may harm the fetus.

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