Clofibrate, an anticholesteremic drug
Brand name: Atromid-S
Uses
The medication is used to treat elevated cholesterol and triglyceride (fatty acid compound) levels in the blood.
Clofibrate is ethyl ester of clofibric acid. It has the role of an anticholesteremic drug, an antilipemic drug, a geroprotector and a PPAR alpha agonist. It is an aromatic ether, a member of mono chlorobenzenes and an ethyl ester. It is functionally related to clofibric acid.
IUPAC name: ethyl 2-(4-chlorophenoxy)-2-methyl propanoate
Drug Class: Antihyperlipidemic drug
Route of administration: Oral
This is a prescribed drug and not an OTC drug
Drug Mechanism Action
Clofibrate is a lipoprotein lipase activator. As it increases lipoprotein lipase activity, it reduces VLDL levels by converting them to LDL.
Adverse effects
Headache, nausea, fatigue, stomach discomfort, weakness, lack of appetite, rapid weight gain, and muscular soreness are possible adverse effects of clofibrate.
Precautions
It is advisable to consult a doctor or physician before taking this medication.
- If the person is allergic to the drug or has any other allergies
- If the person is taking any medication (i.e., prescribed, non-prescribed or any herbal medication)
- If the person is suffering from hepatic disease, renal issues, diabetes, stomach/ intestinal ulcer, thyroid disorder, gallbladder disease
- While taking this drug, avoid alcohol consumption because it elevates the chance of developing hepatic issues.
- If the person has undergone any type of eye surgery or dental surgery.
- This medication is not recommended for pregnant and breastfeeding women. Clofibrate is not advisable for kids under the age of 2 years.
