Cetrorelix

March 30, 2022

1 minute read

USES
Cetrorelix is mainly used to manage ovarian hyperstimulation which helps in fertility treatments.

IUPAC name: (2S)-1-[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2R)-2-[[(2R)-2-acetamido-3-naphthalen-2-ylpropanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-3-pyridin-3-ylpropanoyl]amino]-3-hydroxypropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-5-(carbamoylamino)pentanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2R)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamide

Drug class: Gonadotropin Releasing Hormone Antagonists
Is it a drug that needs a prescription? YES
Is it an OTC drug? NO

Mechanism of action
Cetrorelix works by inhibiting the release of luteinizing hormone. Thus, preventing premature ovulation (early release of eggs from the ovaries).

Side effects
Common side effects may include headache, vomiting, pain/swelling at injection site.

Serious side effects may include severe pain/swelling in the pelvic area, rash/itching, dizziness, decreased urination, fast weight gain, omitting/nausea.

It may cause a condition called ovarian hyperstimulation syndrome (OHSS).

Precautions
Following precautions should be taken before using this medication:

If you are allergic to GnRH medications or if you have any other allergies.

If you have a medical history of kidney disease or allergic reactions.
This medication should not be used during pregnancy.