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Calcitonin

USES:
The following underlying conditions are treated with calcitonin:

  • Osteoporosis in women after menopause
  • Paget’s disease of bone
  • Hypercalcemia

IUPAC name: H-Cys(1)-Ser-Asn-Leu-Ser-Thr-Cys(1)-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2

Route of administration: Intranasal, Subcutaneous, Intramuscular

Is it a drug that needs a prescription? YES

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Is it an OTC drug? NO

Mechanism of action

Calcitonin works by inhibiting the activity of osteoclasts (bone resorption) and supporting osteoblasts in bone formation. As a result, it facilitates the prevention of bone density loss and therefore aids in the restoration of blood calcium levels.

Adverse effects

Dizziness, a salty taste in the mouth, and nasal irritation/dryness may occur when this medication is administered by nasal route.

Nausea, vomiting, redness/irritation/swelling at the injection site, abdominal cramps, muscle cramps, and flushing are possible side effects when administered by injection.

Precautions

Before using this medication, take the following precautions and notify your doctor:

  • If you are allergic to it or if you have any other allergies.
  • If you have a medical history of hypocalcemia (low level of calcium in blood)
  • If you are pregnant.

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