This drug is used to treat generalized anxiety disorder (GAD) and for short-term treatment of anxiety.

IUPAC name: 8-[4-(4-pyrimidin-2-yl piperazin-1-yl)butyl]-8-azaspiro[4.5]decane-7,9-dione

Drug class:  Anxiolytics (Anti-anxiety drugs)

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Route of administration: Oral

Is it a drug that needs a prescription? YES

Is it an OTC drug? NO

Mechanism of action

Buspirone affects the serotonin, a chemical messenger (neurotransmitter) in the brain. This medication works by increasing the action of serotonin receptors, which helps to reduce anxiety.

Side effects

It may cause dizziness, drowsiness, diarrhea, lightheadedness, insomnia, nervousness, confusion, nausea, vomiting, fatigue, weakness, fainting, lack of coordination, chest pain, tremor, abnormally fast heart rate, rash/itching, vision changes. 


Before using this medication, take the following precautions and notify your doctor:

If you are allergic to it, or if you have other allergies,

If you are taking any other medication (prescribed, non-prescribed, or herbal products),

When you have a history of liver disease, kidney disease, bipolar disorder, Parkinson’s disease drug abuse,

If you have undergone any type of surgery,

Use of this medication should not be stopped abruptly without consulting your doctor.

Limit your alcohol usage since it increases your chances of developing blurred vision, dizziness, or drowsiness. It may also cause a loss of alertness.

The side effects of this drug may be more severe among older adults (above 65).

Use of this medication should be avoided during pregnancy or breastfeeding.

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