Brexanolone
Uses
This medication is mainly used in women for the treatment of postpartum depression.
IUPAC name: 1-[(3R,5S,8R,9S,10S,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetra decahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone
Drug class: Neuroactive steroid GABA-A Modulator Antidepressant
Route of administration: Intravenous
Is it a drug that needs a prescription? YES
Is it an OTC drug? NO
Mechanism of action
This medication works by modulating the GABA-A receptor, which improves mood or decreases anxiety, thereby restoring mental balance.
Side effects
Brexanolone commonly causes dizziness/ drowsiness, dry mouth, flushing, sedation, and loss of consciousness.
Precautions
Before taking this medication, take the following precautions and notify your doctor:
-If you are allergic to it, any other medicine, or if you have other allergies
-If you are taking other medications (including prescription medicine, nonprescription medicine, or herbal products),
-Avoid alcohol consumption as it makes you more drowsy
-This medication is normally avoided during pregnancy since it can harm the fetus.
-It should be used after the baby is born.
-Consult your doctor if you intend to use this medicine while breastfeeding.